Jan Philipp Bittner, M.Sc.

Research

Rational Analysis of Structural and Functional Changes of Oxidoreductases in Non-Conventional Reaction Media
Design of Redox Biocatalysis in Deep Eutectic Solvents (DESiRE)

Teaching

Applied Thermodynamics: Thermophysical Properties for Industrial Applications (winter term)

Articles

2024

Integrated preservation of water activity as key to intensified chemoenzymatic synthesis of bio-based styrene derivatives
Petermeier, Philipp; Bittner, Jan Philipp; Jonsson, Tobias; Domínguez de María, Pablo; Byström, Emil; Kara, Selin
Communications Chemistry 7 (1): 57 (2024)
Open Access | Publisher DOI
Investigating biomolecules in deep eutectic solvents with molecular dynamics simulations : current state, challenges and future perspectives
Bittner, Jan Philipp; Smirnova, Irina; Jakobtorweihen, Sven
Molecules 29 (3): 703 (2024)
Open Access | Publisher DOI

2023

Deep Eutectic Solvents for the Enzymatic Synthesis of Sugar Esters: A Generalizable Strategy?
Semproli, Riccardo; Chanquia, Santiago Nahuel; Bittner, Jan Philipp; Müller, Simon; Domínguez de María, Pablo; Kara, Selin; Ubiali, Daniela
ACS Sustainable Chemistry and Engineering 11 (15): (2023-04-17)
Open Access | Publisher DOI

2022

Design of a green chemoenzymatic cascade for scalable synthesis of bio-based styrene alternatives
Petermeier, Philipp; Bittner, Jan Philipp; Müller, Simon; Byström, Emil; Kara, Selin
Green Chemistry 24: 6889-6899 (2022)
Open Access | Publisher DOI
Unraveling Alcohol Dehydrogenase Catalysis in Organic-Aqueous Biphasic Systems Combining Experiments and Molecular Dynamics Simulations
Zhang, Ningning; Bittner, Jan Philipp; Fiedler, Marius; Beretta, Thomas; Domínguez de María, Pablo; Jakobtorweihen, Sven; Kara, Selin
ACS Catalysis 12 (15): 9171-9180 (2022-08-05)
Open Access | Publisher DOI
Impact of deep eutectic solvents (DESs) and individual des components on alcohol dehydrogenase catalysis: connecting experimental data and molecular dynamics simulations
Bittner, Jan Philipp; Zhang, Ningning; Huang, Lei; Domínguez de María, Pablo; Jakobtorweihen, Sven; Kara, Selin
Green Chemistry 24 (3): 1120-1131 (2022-02-07)
Open Access | Publisher DOI

2021

Comparison and Validation of Force Fields for Deep Eutectic Solvents in Combination with Water and Alcohol Dehydrogenase
Bittner, Jan Philipp; Huang, Lei; Zhang, Ningning; Kara, Selin; Jakobtorweihen, Sven
Journal of Chemical Theory and Computation 17 (8): 5322-5341 (2021-08-10)
Open Access | Publisher DOI

2020

Modeling alcohol dehydrogenase catalysis in deep eutectic solvent/water mixtures
Huang, Lei; Bittner, Jan Philipp; Domínguez de María, Pablo; Jakobtorweihen, Sven; Kara, Selin
ChemBioChem 6 (21): 811-817 (2020-03-16)
Open Access | Publisher DOI
Thermodynamic and transport properties modeling of deep eutectic solvents: a review on gE-models, equations of state, and molecular dynamics
González de Castilla, Andrés; Bittner, Jan Philipp; Müller, Simon; Jakobtorweihen, Sven; Smirnova, Irina
Journal of Chemical and Engineering Data 3 (65): 943-967 (2020)
Open Access | Publisher DOI

Presentations

Thermodynamic modelling of the swelling behaviour of stimuli-responsive gels in multicomponent systems using PC-SAFT
K. Eckert; J. Bittner; S. Müller; X. Hu; I. Smirnova; W. Chapman, MSML Conference, Cologne, Germany (2023)
Novel insights into the behavior of alcohol dehydrogenase in deep eutectic solvents: a molecular dynamics study
J. Bittner; N. Zhang; L. Huang; P. Domínguez de María; S. Kara; S. Jakobtorweihen, 13th European Congress of Chemical Engineering and 6th European Congress of Applied Biotechnology, digital (2021)
Novel insights into the behavior of alcohol dehydrogenase in deep eutectic solvents: a molecular dynamics study
J. Bittner; N. Zhang; L. Huang; P. Domínguez de María; S. Kara; S. Jakobtorweihen, Himmelfahrtstagung on Bioprocess Engineering 2021 - New Bioprocesses, New Bioproducts, digital (2021)
Novel insights into the behavior of alcohol dehydrogenase in deep eutectic solvents: a molecular dynamics study
J. Bittner; N. Zhang; L. Huang; P. Domínguez de María; S. Kara; S. Jakobtorweihen, Biocatalysis in Non-Conventional Media – BNCM 2021, Milan (Italy) (2021)
Novel insights into the behavior of alcohol dehydrogenase in deep eutectic solvents: a molecular dynamics study
J. Bittner; L. Huang; N. Zhang; P. Domínguez de María; S. Kara; S. Jakobtorweihen, International Workshop on Molecular Modeling and Simulation, Frankfurth am Main, (Germany) (2021)
Molecular dynamics simulations of alcohol dehydrogenase in the deep eutectic solvent glyceline
J. Bittner; L. Huang; S. Kara; I. Smirnova; S. Jakobtorweihen, 7th Workshop of Integrated Biotechnology and Process Engineering, Hamburg (Germany) (2019)