Multi-Patch Sequences in Magnetic Particle Imaging

In this project we develop multi-patch imaging sequences and reconstruction algorithms for enlarged measuring fields in magnetic particle imaging (MPI). The regular field-of-view (FOV) in MPI is limited due to physiological constraints such as tissue heating and nerve stimulation. In practice typical FOV are in the range of 2x2x1 cm³. In order to scan larger regions it is possible to shift the FOV to different positions and scan various smaller FOV, which can later be combined to a joint 3D dataset. Especially the reconstruction of multi-patch data is a computationally intensive and memory demanding task. In this project we develop algorithms for efficient reconstruction of multi-patch MPI data.

To reduce calibration time and speed up image reconstruction, we have introduced a number of different methods, including reducing the number of system matricessystem matrix warping, and overscan extrapolation.

Sketch of a multi-patch imaging sequence.

Publications

  • K. Scheffler, M. Boberg, and T. Knopp (2023). Extrapolation of System Matrices in Magnetic Particle Imaging. IEEE Transactions on Medical Imaging. 42. (4), 1121 - 1132 [Abstract] [pdf] [doi]

  • M. Boberg, T. Knopp, and M. Möddel (2023). Reducing displacement artifacts in multi-patch magnetic particle imaging. 10th International Congress on Industrial and Applied Mathematics (ICIAM 2023). 05026 [Abstract] [www]

  • K. Scheffler, M. Boberg, and T. Knopp (2022). Boundary artifact reduction by extrapolating system matrices outside the field-of-view in joint multi-patch MPI. International Journal on Magnetic Particle Imaging. 8. (1), 1-3 [Abstract] [doi] [www]

  • L. Zdun, M. Boberg, and C. Brandt (2022). Fast and artifact reducing joint multi-patch MPI reconstruction. International Journal on Magnetic Particle Imaging. 8. (1), 1-4 [Abstract] [doi] [www]

  • L. Zdun, M. Boberg, and C. Brandt (2022). Joint multi-patch reconstruction: fast and improved results by stochastic optimization. International Journal on Magnetic Particle Imaging. 8. (2), 1-8 [Abstract] [doi] [www]

  • M. Boberg, N. Gdaniec, M. Möddel, P. Szwargulski, and T. Knopp (2022). Suppression of Motion Artifacts in Multi-Patch Magnetic Particle Imaging of a Phantom with Periodic Motion. SIAM Conference on Imaging Science (IS22). [Abstract]

  • P. Szwargulski, T. Knopp, M. Boberg, J. Salamon, V. Scheitenberger, T. Göttsche, R. Linemann, F. Wegner, T. Friedrich, J. Barkhausen, T. M. Buzug, and M. Ahlborg (2022). First Complex Trials Using a Dedicated Balloon Catheter for Magnetic Particle Imaging. International Journal on Magnetic Particle Imaging. 8. (1), 1-4 [Abstract] [doi] [www]

  • M. Boberg, T. Knopp, and M. Möddel (2020). Reducing displacement artifacts by warping system matrices in efficient joint multi-patch magnetic particle imaging. International Journal on Magnetic Particle Imaging. 6. (2), 1-3 [Abstract] [doi] [www]

  • M. Boberg, T. Knopp, P. Szwargulski, and M. Möddel (2020). Generalized MPI Multi-Patch Reconstruction using Clusters of similar System Matrices. IEEE Transactions on Medical Imaging. 39. (5), 1347-1358 [Abstract] [doi] [www]

  • N. Gdaniec, M. Boberg, M. Möddel, P. Szwargulski, and T. Knopp (2020). Suppression of Motion Artifacts Caused by Temporally Recurring Tracer Distributions in Multi-Patch Magnetic Particle Imaging. IEEE Transactions on Medical Imaging. 39. (11), 3548-3558 [Abstract] [doi] [www]

  • M. Boberg, M. Möddel, and T. Knopp (2019). Magnetic field based system matrix corrections for multi-patch MPI reconstructions. 9th International Congress on Industrial and Applied Mathematics (ICIAM 2019). 333 [Abstract] [www]

  • M. Boberg, T. Knopp, and M. Möddel (2019). Magnetic Field Based Similarity Measure for System Matrices in Magnetic Particle Imaging. 9th International Workshop on Magnetic Particle Imaging (IWMPI 2019). 73-74 [Abstract]

  • P. Szwargulski, M. Möddel, N. Gdaniec and T. Knopp (2019). Efficient Joint Image Reconstruction of Multi-Patch Data reusing a Single System Matrix in Magnetic Particle Imaging. IEEE Transactions on Medical Imaging. 38. (4), 932-944 [Abstract] [doi] [www]

  • M. Ahlborg, C. Kaethner, P. Szwargulski, T. Knopp, T. M. Buzug (2018). Reusing System Matrices of Patches in Magnetic Particle Imaging via Mirroring. 8th International Workshop on Magnetic Particle Imaging (IWMPI 2018) 51-52

  • M. Ahlborg, C. Kaethner, P. Szwargulski, T. Knopp, T. M. Buzug (2018). Patches in Magnetic Particle Imaging. BVM Workshop 2018 169

  • P. Szwargulski, N. Gdaniec, M. Graeser, M. Möddel, F. Griese, K. M. Krishnan, T. M. Buzug, and T. Knopp (2018). Moving table magnetic particle imaging: a stepwise approach preserving high spatio-temporal resolution. Journal of Medical Imaging. 5. (4), 046002 [Abstract] [doi] [www]

  • P. Szwargulski, N. Gdaniec, M. Graeser, M. Möddel, F. Griese, T. Knopp (2018). Erweiterung des Bildgebungsbereiches bei der Magnetpartikelbildgebung durch externe axiale Verschiebungen. BVM Workshop 2018 202 [Abstract]

  • P. Szwargulski, N. Gdaniec, M. Graeser, M. Möddel, F. Griese, T. Knopp (2018). Enlarging the field of view in magnetic particle imaging using a moving table approach. 10578 - 10578 - 7 [Abstract] [doi] [www]

  • P. Szwargulski, N. Gdaniec, M. Möddel , M. Graeser, T. Knopp (2018). Reconstruction of an object moved continuously through the Field of View in MPI. 8th International Workshop on Magnetic Particle Imaging (IWMPI 2018) 137-138

  • P. Szwargulski, N. Gdaniec, T. Knopp (2018). Schnelle adaptive Aufnahme von Magnetic-Particle-Imaging Daten durch Nutzung mehrerer Gradientenstärken. BVM Workshop 2018 373 [Abstract]

  • N. Gdaniec, P. Szwargulski, and T. Knopp (2017). Fast Multi-Resolution Data Acquisition for Magnetic Particle Imaging using Adaptive Feature Detection. Medical Physics. 44. (12), 6456-6460 [doi] [www]

  • A. Weber, F. Werner, J. Weizenecker, T. M. Buzug, T. Knopp (2016). Artifact free reconstruction with the system matrix approach by overscanning the field-free-point trajectory in magnetic particle imaging. Phys. Med. Biol.. 61. (2), 475-487 [doi]

  • M. Ahlborg, C. Kaethner, T. Knopp, P Szwargulski, T. Buzug (2016). Using data redundancy gained by patch overlaps to reduce truncation artifacts in magnetic particle imaging. Phys. Med. Biol.. 61. (12), 4583–4598

  • P. Szwargulski, M. Hofmann, N. Gdaniec and T. Knopp (2016). Fast Implicit Reconstruction of Focus Field Data in MPI. 6th International Workshop on Magnetic Particle Imaging (IWMPI 2016) 176

  • P. Szwargulski, M. Hofmann, N. Gdaniec, T. Knopp (2016). The Influence of Field Distortions on Multi-Patch Image Reconstruction in Magnetic Particle Imaging.

  • T. Knopp and M.G. Kaul (2015). MPI focus field experiments using non-overlapping focus-field patches. 1pp

  • T. Knopp, K. Them, F. Werner, M. Hofmann (2015). Reusing System Matrices at different Focus Field Positions in Magnetic Particle Imaging. S1

  • T. Knopp, K. Them, M. Kaul and N. Gdaniec (2015). Joint reconstruction of non-overlapping magnetic particle imaging focus-field data. Phys. Med. Biol.. 60. L15 [doi]