Requirements for cell culture processess, shear effects, microcarrier technology Reactor systems for mammalian cell culture (production systems) (design, layout, scale-up: suspension reactors (stirrer, aeration, cell retention), fixed bed, fluidized bed (carrier), hollow fiber reactors (membranes), dialysis reactors, Reactor systems for Tissue Engineering, Prozess strategies (batch, fed-batch, continuous, perfusion, mathematical modelling), control (oxygen, substrate etc.) • Downstream
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