IBI: Clinical Surveillance MPI Scanner for Stroke Units

Surveillance MPI Scanner for Stroke Detection on the Intensive Care Stroke Unit

Scientists at the Technical University of Hamburg (TUHH) and the University Hospital Hamburg-Eppendorf (UKE) have developed a new diagnostic tomographic imaging system that enables access to cerebral blood flow at short intervals and thus quickly indicates a possible stroke. The study "Human-sized Magnetic Particle Imaging for Brain Applications" was published on the 26th of April 2019 in the renowned journal Nature Communications.

On the road to full real-time 3D imaging using approved clinical tracers, the MPI scanner has been extensively upgraded from 2019 to 2023. Several publications document the process and highlight the development of new components, like the study "Heat it up: Thermal stabilization by active heating to reduce impedance drifts in capacitive matched networks", "Gradient power reducing using pulsed selection-field sequences" or "Resonant inductive coupling network for human-sized magnetic particle imaging". A thorough exploration is presented in "System characterization of a human-sized 3D real-time magnetic particle imaging scanner for cerebral applications".

Prof. Tobias Knopp and Dr. Matthias Gräser with the surveillance imager

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[120377]

Title: Stroke Detection using Magnetic Particle Imaging: A Phantom Study using a Human-sized Brain Phantom. <em>9th International Workshop on Magnetic Particle Imaging (IWMPI 2019)</em>

Written by: F. Werner, M. Gräser, F. Thieben, P Szwargulski, N. Gdaniec, M. Boberg, F. Griese, M. Möddel, P. Ludewig, D. van de Ven, O. M. Weber, O. Woywode, B. Gleich, and T. Knopp

in: (2019).

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on pages: 141-142

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Note: inproceedings, brainimager

Abstract: The determination of brain perfusion is essential for rapid diagnosis and therapy of vascular diseases such as an acute stroke. Due to the potential risk of restenosis, the patient must be closely monitored the days after treatment. Recently, the first human-sized magnetic particle imager for brain applications has been introduced. In comparison to conventional techniques, the technical realization of the device allows for the use on intensive care units making repetitive monitoring possible. In this work, a human-sized brain phantom was designed and measurements were performed to prove the suitability of the device for visualizing perfusion deficits.

Surveillance MPI Scanner for Stroke Detection on the Intensive Care Stroke Unit

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