Prof. Dr.-Ing. Tobias Knopp

Universitätsklinikum Hamburg-Eppendorf (UKE)
Sektion für Biomedizinische Bildgebung
Lottestraße 55
2ter Stock, Raum 209
22529 Hamburg
- Postanschrift -

Technische Universität Hamburg (TUHH)
Institut für Biomedizinische Bildgebung
Gebäude E, Raum 4.044
Am Schwarzenberg-Campus 3
21073 Hamburg

Tel.: 040 / 7410 56794
Fax: 040 / 7410 45811
E-Mail: t.knopp(at)uke.de
E-Mail: tobias.knopp(at)tuhh.de
ORCID: https://orcid.org/0000-0002-1589-8517

 

Roles

  • Head of the Institute for Biomedical Imaging
  • Editor-in-chief of the International Journal on Magnetic Particle Imaging (IJMPI)

Consulting Hours

  • On appointment

Research Interests

  • Tomographic Imaging
  • Image Reconstruction
  • Signal- and Image Processing
  • Magnetic Particle Imaging

Curriculum Vitae

Tobias Knopp received his Diplom degree in computer science in 2007 and his PhD in 2010, both from the University of Lübeck with highest distinction. For his PHD on the tomographic imaging method Magnetic Particle Imaging (MPI) he was awarded with the Klee award from the DGBMT (VDE) in 2011. From 2010 until 2011 he led the MAPIT project at the University of Lübeck and published the first scientific book on MPI. In 2011 he joined Bruker Biospin to work on the first commercially available MPI system. From 2012 until 2014 he worked at Thorlabs in the field of Optical Coherence Tomography (OCT) as a software developer. In 2014 he has been appointed as Professor for experimental Biomedical Imaging at the University Medical Center Hamburg-Eppendorf and the Hamburg University of Technology.

Publications

[191156]
Title: Sparse Kaczmarz for Convergence Speed-up in Multi-Contrast Magnetic Particle Imaging.
Written by: L. Nawwas, M. Möddel, T. Knopp
in: <em>IEEE INTERNATIONAL SYMPOSIUM ON BIOMEDICAL IMAGING (ISBI 2024)</em>. (2024).
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Note: inproceedings, multi-contrast

Abstract: Magnetic Particle Imaging (MPI) is a tracer-based medical imaging modality with great potential due to its high sensitivity, high spatio-temporal resolution, and capability to quantify the tracer distribution. Image reconstruction in MPI is an ill-posed problem, which regularization methods can address. In MPI, Tikhonov regularization is most commonly used and the corresponding optimization problem is usually solved using the Kaczmarz algorithm. Reconstruction using the Kaczmarz method for single-contrast MPI is very efficient as it produces the desired images fast after a small number of iterations. For multi-contrast MPI, however, the regular Kaczmarz algorithm fails to obtain good-quality images without channel leakage when using a small number of iterations. In this work, we propose a sparsity-promoting regularization term and an associated sparse Kaczmarz method in order to speed up convergence, especially in sparse channels. The proposed method reduces the channel leakage and as a result, speeds up convergence.