[76909] |
Title: Imaging Characterization of {MPI} Tracers Employing Offset Measurements in a two Dimensional Magnetic Particle Spectrometer. |
Written by: D. Schmidt, M. Graeser, A. von Gladiss, T.M. Buzug, and U. Steinhoff |
in: <em>International Journal on Magnetic Particle Imaging</em>. (2016). |
Volume: <strong>2</strong>. Number: (1), |
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DOI: 10.18416/ijmpi.2016.1604002 |
URL: https://journal.iwmpi.org/index.php/iwmpi/article/view/24 |
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Note: article
Abstract: We developed a method to characterize the imaging performance of {MPI} tracers from virtual {MPI} measurements that can be synthesized using measurement data from a Magnetic Particle Spectrometer ({MPS}) at different static magnetic field offsets. {MPI} system functions were obtained from measurements on a {FeraSpin}™ R ({nanoPET} {GmbH}, Berlin) sample in a 2D {MPS} comprising two excitation coils and two receive coils. Software phantoms of spatial {MPI} tracer distributions with different size and shape were constructed. With the measured {MPI} system function, a synthetic {MPI} measurement of the software phantoms was simulated. By adding noise to the virtual {MPI} data, the detection limit of each harmonic in dependence of the noise level was obtained. An {MPI} reconstruction of the virtual tracer distribution was performed using the virtual {MPI} data as input. By comparing the reconstructed images with the actual software phantoms, we obtained the spatial resolution of {MPI} of the investigated tracers. This method might help predicting the image resolution for real {MPI} setups. Our characterization method provides a valuable link between pure spectroscopic characterization and time consuming {MPI} phantom experiments.
[76909] |
Title: Imaging Characterization of {MPI} Tracers Employing Offset Measurements in a two Dimensional Magnetic Particle Spectrometer. |
Written by: D. Schmidt, M. Graeser, A. von Gladiss, T.M. Buzug, and U. Steinhoff |
in: <em>International Journal on Magnetic Particle Imaging</em>. (2016). |
Volume: <strong>2</strong>. Number: (1), |
on pages: |
Chapter: |
Editor: |
Publisher: |
Series: |
Address: |
Edition: |
ISBN: |
how published: |
Organization: |
School: |
Institution: |
Type: |
DOI: 10.18416/ijmpi.2016.1604002 |
URL: https://journal.iwmpi.org/index.php/iwmpi/article/view/24 |
ARXIVID: |
PMID: |
Note: article
Abstract: We developed a method to characterize the imaging performance of {MPI} tracers from virtual {MPI} measurements that can be synthesized using measurement data from a Magnetic Particle Spectrometer ({MPS}) at different static magnetic field offsets. {MPI} system functions were obtained from measurements on a {FeraSpin}™ R ({nanoPET} {GmbH}, Berlin) sample in a 2D {MPS} comprising two excitation coils and two receive coils. Software phantoms of spatial {MPI} tracer distributions with different size and shape were constructed. With the measured {MPI} system function, a synthetic {MPI} measurement of the software phantoms was simulated. By adding noise to the virtual {MPI} data, the detection limit of each harmonic in dependence of the noise level was obtained. An {MPI} reconstruction of the virtual tracer distribution was performed using the virtual {MPI} data as input. By comparing the reconstructed images with the actual software phantoms, we obtained the spatial resolution of {MPI} of the investigated tracers. This method might help predicting the image resolution for real {MPI} setups. Our characterization method provides a valuable link between pure spectroscopic characterization and time consuming {MPI} phantom experiments.