Dr. rer. nat. Martin Möddel (Hofmann)

Universitätsklinikum Hamburg-Eppendorf (UKE)
Sektion für Biomedizinische Bildgebung
Lottestraße 55
2ter Stock, Raum 212
22529 Hamburg
- Postanschrift -

Technische Universität Hamburg (TUHH)
Institut für Biomedizinische Bildgebung
Gebäude E, Raum 4.044
Am Schwarzenberg-Campus 3
21073 Hamburg

Tel.: 040 / 7410 56309
E-Mail: martin.moeddel(at)tuhh.de
E-Mail: m.hofmann(at)uke.de
ORCID: https://orcid.org/0000-0002-4737-7863

Research Interests

My research on tomographic imaging is primarily focused on magnetic particle imaging. In this context, I am engaged in the study of a number of problems, including:

  • Image reconstruction
    • Multi-contrast imaging
    • Multi-patch imaging
    • Artifact reduction
  • Magnetic field generation and characterisation
  • Receive path calibration

Curriculum Vitae

Martin Möddel is a postdoctoral researcher in the group of Tobias Knopp for experimental Biomedical Imaging at the University Medical Center Hamburg-Eppendorf and the Hamburg University of Technology. He received his PhD in physics from the Universität Siegen in 2014 on the topic of characterizing quantum correlations: the genuine multiparticle negativity as entanglement monotone. Prior to his PhD, he studied physics at the Universität Leipzig between 2005 and 2011, where he received his Diplom On the costratified Hilbert space structure of a lattice gauge model with semi-simple gauge group.

Journal Publications

[183660]
Title: Using Negative Bolus in Dynamic MPI.
Written by: F. Mohn, M. Exner, P. Szwargulski, M. Möddel, T. Knopp, and M. Graeser
in: <em>International Journal on Magnetic Particle Imaging IJMPI</em>. mar (2023).
Volume: Number:
on pages: 9.(1).
Chapter:
Editor:
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Edition:
ISBN:
how published:
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DOI: 10.18416/IJMPI.2023.2303022
URL: https://journal.iwmpi.org/index.php/iwmpi/article/view/579
ARXIVID:
PMID:

[www] [BibTex]

Note: inproceedings

Abstract: In Magnetic Particle Imaging, the spatial distribution of a tracer is measured and depicted with a concentration dependent signal intensity for any location that inhibits particles, whereas surrounding tissue does not provide any signal. After tracer injection, the signal over time (positive contrast) can be utilized as a transient response to calculate dynamic diagnostic parameters like perfusion parameter maps. In this work, a bolus of physiological saline solution without any particles (negative contrast) is proposed, where the remaining steady state concentration contributes to the image contrast. This opens up the possibility to stretch the total monitoring time of a patient by utilizing a positive-negative contrast sequence, while keeping the total iron dose constant in the subject. Resulting time responses show that normalized signals from positive and negative boli are concurrent in the phantom experiments, indicating identical diagnostic parameters for in-vivo use.

[183660]
Title: Using Negative Bolus in Dynamic MPI.
Written by: F. Mohn, M. Exner, P. Szwargulski, M. Möddel, T. Knopp, and M. Graeser
in: <em>International Journal on Magnetic Particle Imaging IJMPI</em>. mar (2023).
Volume: Number:
on pages: 9.(1).
Chapter:
Editor:
Publisher:
Series:
Address:
Edition:
ISBN:
how published:
Organization:
School:
Institution:
Type:
DOI: 10.18416/IJMPI.2023.2303022
URL: https://journal.iwmpi.org/index.php/iwmpi/article/view/579
ARXIVID:
PMID:

[www] [BibTex]

Note: inproceedings

Abstract: In Magnetic Particle Imaging, the spatial distribution of a tracer is measured and depicted with a concentration dependent signal intensity for any location that inhibits particles, whereas surrounding tissue does not provide any signal. After tracer injection, the signal over time (positive contrast) can be utilized as a transient response to calculate dynamic diagnostic parameters like perfusion parameter maps. In this work, a bolus of physiological saline solution without any particles (negative contrast) is proposed, where the remaining steady state concentration contributes to the image contrast. This opens up the possibility to stretch the total monitoring time of a patient by utilizing a positive-negative contrast sequence, while keeping the total iron dose constant in the subject. Resulting time responses show that normalized signals from positive and negative boli are concurrent in the phantom experiments, indicating identical diagnostic parameters for in-vivo use.

Conference Proceedings

[183660]
Title: Using Negative Bolus in Dynamic MPI.
Written by: F. Mohn, M. Exner, P. Szwargulski, M. Möddel, T. Knopp, and M. Graeser
in: <em>International Journal on Magnetic Particle Imaging IJMPI</em>. mar (2023).
Volume: Number:
on pages: 9.(1).
Chapter:
Editor:
Publisher:
Series:
Address:
Edition:
ISBN:
how published:
Organization:
School:
Institution:
Type:
DOI: 10.18416/IJMPI.2023.2303022
URL: https://journal.iwmpi.org/index.php/iwmpi/article/view/579
ARXIVID:
PMID:

[www] [BibTex]

Note: inproceedings

Abstract: In Magnetic Particle Imaging, the spatial distribution of a tracer is measured and depicted with a concentration dependent signal intensity for any location that inhibits particles, whereas surrounding tissue does not provide any signal. After tracer injection, the signal over time (positive contrast) can be utilized as a transient response to calculate dynamic diagnostic parameters like perfusion parameter maps. In this work, a bolus of physiological saline solution without any particles (negative contrast) is proposed, where the remaining steady state concentration contributes to the image contrast. This opens up the possibility to stretch the total monitoring time of a patient by utilizing a positive-negative contrast sequence, while keeping the total iron dose constant in the subject. Resulting time responses show that normalized signals from positive and negative boli are concurrent in the phantom experiments, indicating identical diagnostic parameters for in-vivo use.

[183660]
Title: Using Negative Bolus in Dynamic MPI.
Written by: F. Mohn, M. Exner, P. Szwargulski, M. Möddel, T. Knopp, and M. Graeser
in: <em>International Journal on Magnetic Particle Imaging IJMPI</em>. mar (2023).
Volume: Number:
on pages: 9.(1).
Chapter:
Editor:
Publisher:
Series:
Address:
Edition:
ISBN:
how published:
Organization:
School:
Institution:
Type:
DOI: 10.18416/IJMPI.2023.2303022
URL: https://journal.iwmpi.org/index.php/iwmpi/article/view/579
ARXIVID:
PMID:

[www] [BibTex]

Note: inproceedings

Abstract: In Magnetic Particle Imaging, the spatial distribution of a tracer is measured and depicted with a concentration dependent signal intensity for any location that inhibits particles, whereas surrounding tissue does not provide any signal. After tracer injection, the signal over time (positive contrast) can be utilized as a transient response to calculate dynamic diagnostic parameters like perfusion parameter maps. In this work, a bolus of physiological saline solution without any particles (negative contrast) is proposed, where the remaining steady state concentration contributes to the image contrast. This opens up the possibility to stretch the total monitoring time of a patient by utilizing a positive-negative contrast sequence, while keeping the total iron dose constant in the subject. Resulting time responses show that normalized signals from positive and negative boli are concurrent in the phantom experiments, indicating identical diagnostic parameters for in-vivo use.