Introduction to Biosystems Engineering

Experimental basis and methods for biosystems analysis

• Introduction to genomics, transcriptomics and proteomics
• More detailed treatment of metabolomics
• Determination of in-vivo kinetics
• Techniques for rapid sampling
• Quenching and extraction
• Analytical methods for determination of metabolite concentrations

Analysis, modelling and simulation of biological networks

• Metabolic flux analysis
• Introduction
• Isotope labelling
• Elementary flux modes
• Mechanistic and structural network models
• Regulatory networks
• Systems analysis
• Structural network analysis
• Linear and non-linear dynamic systems
• Sensitivity analysis (metabolic control analysis)

Modelling and simulation for bioprocess engineering

• Modelling of bioreactors
• Dynamic behaviour of bioprocesses 

Selected projects for biosystems engineering

• Miniaturisation of bioreaction systems
• Miniplant technology for the integration of biosynthesis and downstream processin
• Technical and economic overall assessment of bioproduction processes