Introduction to Biosystems Engineering
Experimental basis and methods for biosystems analysis
- Introduction to genomics, transcriptomics and proteomics
- More detailed treatment of metabolomics
- Determination of in-vivo kinetics
- Techniques for rapid sampling
- Quenching and extraction
- Analytical methods for determination of metabolite concentrations
Analysis, modelling and simulation of biological networks
- Metabolic flux analysis
- Introduction
- Isotope labelling
- Elementary flux modes
- Mechanistic and structural network models
- Regulatory networks
- Systems analysis
- Structural network analysis
- Linear and non-linear dynamic systems
- Sensitivity analysis (metabolic control analysis)
Modelling and simulation for bioprocess engineering
- Modelling of bioreactors
- Dynamic behaviour of bioprocesses
Selected projects for biosystems engineering - Miniaturisation of bioreaction systems
- Miniplant technology for the integration of biosynthesis and downstream processin
- Technical and economic overall assessment of bioproduction processes
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